HitPredict

Interactor 1: SOCS2 (O88582)
Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2)
Gene: SOCS2

Interactor 2: SOCS2 (O88582)
Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2)
Gene: SOCS2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16956890
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2, SH2~SOCS_box
Common GO terms GO:0005126 - cytokine receptor binding
GO:0005131 - growth hormone receptor binding
GO:0005159 - insulin-like growth factor receptor binding
GO:0005737 - cytoplasm
GO:0007259 - cell surface receptor signaling pathway via JAK-STAT
and 19 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 198
Rn

1 198
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Service provided by Combinatics, Japan

Last updated: 11Aug2025