HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: TBK1 (Q9UHD2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 642 Hs			1 729
+	Hs
		724823 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		IKKE_HUMAN (1-716): 4.07e-146: 445: 48.33
+	Hs
		725161 MYH10_HUMAN (171-636): 1.34e-15: 83.3: 12.84		IKKE_HUMAN (1-716): 4.07e-146: 445: 48.33
+	Hs
		158414 MYH10_HUMAN (171-636): 1.34e-15: 83.3: 12.84		IKKB_HUMAN (9-727): 1.01e-139: 430: 18.98
+	Hs
		167486 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		IKKA_HUMAN (9-637): 4.09e-121: 381: 21.08
+	Hs
		1137917 MRCKB_HUMAN (258-642): 1.73e-21: 102: 12.78		MRCKA_HUMAN (6-698): 6.44e-109: 365: 17.31
+	Hs
		167488 MYH11_HUMAN (180-641): 3.92e-16: 84.8: 12.24		IKKA_HUMAN (9-637): 4.09e-121: 381: 21.08
+	Hs
		167487 MYH10_HUMAN (171-636): 1.34e-15: 83.3: 12.84		IKKA_HUMAN (9-637): 4.09e-121: 381: 21.08
+	Mm
		93554 DESP_MOUSE (190-642): 1.18e-15: 83.5: 15.27		IKKA_MOUSE (9-637): 1.7e-120: 379: 20.94
+	Rn
		222472 MRCKA_RAT (181-627): 1.66e-21: 102: 10.82		MRCKA_RAT (6-698): 5.51e-107: 360: 17.45
+	Hs
		1137871 MRCKA_HUMAN (140-627): 3.84e-19: 94.5: 11.42		MRCKA_HUMAN (6-698): 6.44e-109: 365: 17.31
+	Hs
		625176 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		CDK2_HUMAN (6-312): 1.71e-119: 361: 20.97
+	Rn
		222476 MRCKA_RAT (181-627): 1.66e-21: 102: 10.82		MRCKB_RAT (6-700): 1.94e-103: 349: 15.53
+	Hs
		725010 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		SIK2_HUMAN (9-719): 1.2e-110: 359: 15.54
+	Hs
		625177 MYH10_HUMAN (171-636): 1.34e-15: 83.3: 12.84		CDK2_HUMAN (6-312): 1.71e-119: 361: 20.97
+	Rn
		1186812 MRCKB_RAT (266-642): 2.4e-19: 95.2: 10.61		MRCKB_RAT (6-700): 1.94e-103: 349: 15.53
+	Hs
		728513 MYH11_HUMAN (180-641): 3.92e-16: 84.8: 12.24		SIK2_HUMAN (9-719): 1.2e-110: 359: 15.54
+	Hs
		724967 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MARK4_HUMAN (9-344): 1.37e-86: 290: 24.48
+	Hs
		725223 MYH10_HUMAN (171-636): 1.34e-15: 83.3: 12.84		MARK4_HUMAN (9-344): 1.37e-86: 290: 24.48