HitPredict

Interactor 1: KLF11 (O14901)
Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2)
Gene: KLF11

Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.680

Property	Details
Experiments	11438660, 12006497, 22318730, 15300592
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 1273
+	Hs
		1024877 KLF10_HUMAN (22-483): 6.69e-99: 308: 36.05		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		1302437 KLF16_HUMAN (392-511): 2.97e-37: 139: 60.83		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		1302481 KLF13_HUMAN (389-476): 1.74e-36: 138: 75.00		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		435159 SP1_HUMAN (387-503): 9.79e-34: 137: 55.56		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Mm
		1141061 KLF13_MOUSE (389-476): 2.96e-36: 137: 75.00		SIN3A_MOUSE (1-1273): 0: 1542: 98.04
+	Mm
		250995 SP3_MOUSE (387-482): 2.63e-32: 133: 60.42		SIN3A_MOUSE (1-1273): 0: 1542: 98.04
+	Hs
		1046653 KLF9_HUMAN (389-476): 2.41e-33: 128: 67.05		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		1032224 KLF1_HUMAN (390-477): 1.28e-28: 118: 61.36		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		257826 KLF16_HUMAN (392-511): 2.97e-37: 139: 60.83		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15
+	Hs
		257780 KLF9_HUMAN (389-476): 2.41e-33: 128: 67.05		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15