HitPredict

Interactor 1: GBGT2 (O14610)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 (G gamma-C) (G-gamma-8) (G-gamma-9) (Guanine nucleotide binding protein gamma transducing activity polypeptide 2)
Gene: GNGT2

Interactor 2: GBB3 (P16520)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 (Transducin beta chain 3)
Gene: GNB3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19168127
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005834 - heterotrimeric G-protein complex GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 69 Hs			1 340
+	Hs
		243464 GBG7_HUMAN (5-68): 5.09e-25: 89.3: 40.63		GBB3_HUMAN (1-340): 1.78e-107: 319: 100.00
+	Hs
		597349 GBG2_HUMAN (2-64): 1.99e-24: 88.2: 38.10		GBB3_HUMAN (1-340): 1.78e-107: 319: 100.00
+	Hs
		597375 GBG12_HUMAN (4-68): 3.86e-24: 87.4: 38.46		GBB3_HUMAN (1-340): 1.78e-107: 319: 100.00
+	Hs
		597353 GBG3_HUMAN (3-64): 4.77e-24: 87: 35.48		GBB3_HUMAN (1-340): 1.78e-107: 319: 100.00
+	Hs
		243467 GBG7_HUMAN (5-68): 5.09e-25: 89.3: 40.63		GBB2_HUMAN (1-340): 1.87e-104: 311: 78.49
+	Hs
		948052 GBG2_HUMAN (2-64): 1.99e-24: 88.2: 38.10		GBB2_HUMAN (1-340): 1.87e-104: 311: 78.49
+	Hs
		984316 GBG12_HUMAN (4-68): 3.86e-24: 87.4: 38.46		GBB2_HUMAN (1-340): 1.87e-104: 311: 78.49
+	Hs
		243474 GBG7_HUMAN (5-68): 5.09e-25: 89.3: 40.63		GBB4_HUMAN (1-340): 9.07e-104: 309: 77.33
+	Hs
		948081 GBG2_HUMAN (2-64): 1.99e-24: 88.2: 38.10		GBB4_HUMAN (1-340): 9.07e-104: 309: 77.33
+	Hs
		1437752 GBG12_HUMAN (4-68): 3.86e-24: 87.4: 38.46		GBB4_HUMAN (1-340): 9.07e-104: 309: 77.33
+	Hs
		243466 GBG7_HUMAN (5-68): 5.09e-25: 89.3: 40.63		GBB1_HUMAN (1-340): 8.81e-103: 307: 83.24
+	Hs
		948051 GBG2_HUMAN (2-64): 1.99e-24: 88.2: 38.10		GBB1_HUMAN (1-340): 8.81e-103: 307: 83.24
+	Bt
		983440 GBG2_BOVIN (2-64): 1.99e-24: 88.2: 38.10		GBB1_BOVIN (1-340): 8.81e-103: 307: 83.24
+	Mm
		983624 GBG2_MOUSE (2-64): 1.99e-24: 88.2: 38.10		GBB1_MOUSE (1-340): 8.81e-103: 307: 83.24
+	Hs
		983605 GBG12_HUMAN (4-68): 3.86e-24: 87.4: 38.46		GBB1_HUMAN (1-340): 8.81e-103: 307: 83.24
+	Hs
		983447 GBG3_HUMAN (3-64): 4.77e-24: 87: 35.48		GBB1_HUMAN (1-340): 8.81e-103: 307: 83.24
+	Hs
		163603 GBG7_HUMAN (5-68): 5.09e-25: 89.3: 40.63		GNB5_HUMAN (129-340): 4.38e-45: 160: 21.27
+	Hs
		163627 GBG2_HUMAN (2-64): 1.99e-24: 88.2: 38.10		GNB5_HUMAN (129-340): 4.38e-45: 160: 21.27
+	Hs
		163629 GBG3_HUMAN (3-64): 4.77e-24: 87: 35.48		GNB5_HUMAN (129-340): 4.38e-45: 160: 21.27
+	Hs
		948055 GBG2_HUMAN (2-64): 1.99e-24: 88.2: 38.10		RACK1_HUMAN (97-340): 4.66e-11: 64.7: 27.38