Interactor 1: KMT2D (O14686)
Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2)
Gene: KMT2D
Interactor 2: SET1B (Q9UPS6)
Histone-lysine N-methyltransferase SETD1B (EC 2.1.1.364) (Lysine N-methyltransferase 2G) (SET domain-containing protein 1B) (hSET1B)
Gene: SETD1B
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24981860 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PHD~RRM_1, SET~SET |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032259 - methylation GO:0140945 - histone H3K4 monomethyltransferase activity GO:0140999 - histone H3K4 trimethyltransferase activity |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025