HitPredict

Interactor 1: MPH1 (P40562)
ATP-dependent DNA helicase MPH1 (EC 3.6.4.12) (FANCM-like protein 1) (Mutator phenotype protein 1)
Gene: MPH1

Interactor 2: SMC5 (Q08204)
Structural maintenance of chromosomes protein 5
Gene: SMC5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.742

The method score is based on:

Property Details
Experiments 19995966, 25439736, 27257873, 25956905, 31801080, 21138837
Identification Methods two hybrid, anti tag coimmunoprecipitation, pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000725 - recombinational repair
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0016887 - ATP hydrolysis activity
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 993
Sc

1 1093
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024