HitPredict

Interactor 1: NU145 (G0SAK3)
Nucleoporin NUP145 (EC 3.4.21.-) (Nuclear pore protein NUP145) [Cleaved into: Nucleoporin NUP145N (N-NUP145); Nucleoporin NUP145C (C-NUP145)]
Gene: NUP145

Interactor 2: G0SGZ5 (G0SGZ5)
Importin N-terminal domain-containing protein
Gene: CTHT_0068110

Species: Thermochaetoides thermophila DSM 1495

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26051714
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006606 - protein import into nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1793 Tt			1 938
+	Hs
		916012 NUP98_HUMAN (130-1752): 0: 653: 19.22		TNPO1_HUMAN (2-938): 0: 555: 35.71
+	Hs
		164551 NUP98_HUMAN (130-1752): 0: 653: 19.22		TNPO2_HUMAN (1-938): 3.69e-176: 536: 35.92
+	Hs
		172603 NUP98_HUMAN (130-1752): 0: 653: 19.22		XPO1_HUMAN (13-936): 3.1e-81: 286: 10.41
+	Hs
		915960 NUP98_HUMAN (130-1752): 0: 653: 19.22		IMB1_HUMAN (11-871): 7.14e-77: 271: 16.49
+	Sc
		796100 NU145_YEAST (1303-1788): 8.33e-111: 387: 19.51		IMB2_YEAST (2-872): 7.12e-97: 327: 28.17
+	Sc
		886208 NU145_YEAST (1303-1788): 8.33e-111: 387: 19.51		IMB1_YEAST (11-811): 1.84e-78: 275: 16.71
+	Sc
		734699 NU145_YEAST (1303-1788): 8.33e-111: 387: 19.51		IMB3_YEAST (7-721): 1.21e-42: 170: 18.02
+	Sc
		796113 NU100_YEAST (1-992): 4.37e-34: 145: 18.16		IMB2_YEAST (2-872): 7.12e-97: 327: 28.17
+	Sc
		796114 NU116_YEAST (3-992): 7.22e-27: 121: 17.97		IMB2_YEAST (2-872): 7.12e-97: 327: 28.17
+	Sc
		1037961 NU100_YEAST (1-992): 4.37e-34: 145: 18.16		IMB1_YEAST (11-811): 1.84e-78: 275: 16.71
+	Sc
		1037990 NU116_YEAST (3-992): 7.22e-27: 121: 17.97		IMB1_YEAST (11-811): 1.84e-78: 275: 16.71
+	Hs
		1134327 P121A_HUMAN (5-668): 4.99e-23: 109: 12.43		IMB1_HUMAN (11-871): 7.14e-77: 271: 16.49
+	Sc
		825181 NU159_YEAST (2-469): 2.7e-16: 87.5: 15.68		IMB1_YEAST (11-811): 1.84e-78: 275: 16.71
+	Sc
		734716 NU100_YEAST (1-992): 4.37e-34: 145: 18.16		IMB3_YEAST (7-721): 1.21e-42: 170: 18.02
+	Hs
		1030656 ANK2_HUMAN (130-1367): 8.51e-50: 198: 7.15		ECM29_HUMAN (78-729): 6.17e-19: 95.1: 12.45
+	Sc
		734717 NU116_YEAST (3-992): 7.22e-27: 121: 17.97		IMB3_YEAST (7-721): 1.21e-42: 170: 18.02
+	Sc
		734684 NU159_YEAST (2-469): 2.7e-16: 87.5: 15.68		IMB3_YEAST (7-721): 1.21e-42: 170: 18.02
+	Hs
		274159 ANR17_HUMAN (435-1332): 3.19e-31: 137: 8.22		ECM29_HUMAN (78-729): 6.17e-19: 95.1: 12.45
+	Hs
		133935 MUC1_HUMAN (291-1342): 1.5e-34: 147: 10.41		IPO5_HUMAN (7-587): 9.66e-16: 84.3: 10.58
+	Hs
		134121 P121A_HUMAN (5-668): 4.99e-23: 109: 12.43		IPO5_HUMAN (7-587): 9.66e-16: 84.3: 10.58