HitPredict

Interactor 1: FFAR1 (O14842)
Free fatty acid receptor 1 (G-protein coupled receptor 40)
Gene: FFAR1

Interactor 2: ERD21 (P24390)
ER lumen protein-retaining receptor 1 (KDEL endoplasmic reticulum protein retention receptor 1) (KDEL receptor 1) (Putative MAPK-activating protein PM23)
Gene: KDELR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 300 Hs			1 212
+	Hs
		225369 GPR17_HUMAN (3-295): 1.59e-66: 213: 21.50		ERD23_HUMAN (1-211): 1.51e-83: 248: 72.99
+	Hs
		225373 P2RY8_HUMAN (9-281): 3.71e-66: 212: 25.81		ERD23_HUMAN (1-211): 1.51e-83: 248: 72.99
+	Hs
		664986 P2RY8_HUMAN (9-281): 3.71e-66: 212: 25.81		ERD21_HUMAN (1-212): 1.2e-82: 246: 100.00
+	Hs
		165911 FFAR1_HUMAN (1-300): 3.8e-64: 205: 100.00		ERD22_HUMAN (1-212): 3.5e-85: 252: 83.49
+	Hs
		225367 CXCR4_HUMAN (2-280): 6.66e-64: 206: 20.35		ERD23_HUMAN (1-211): 1.51e-83: 248: 72.99
+	Hs
		165868 FFAR1_HUMAN (1-300): 3.8e-64: 205: 100.00		ERD23_HUMAN (1-211): 1.51e-83: 248: 72.99
+	Hs
		664948 APJ_HUMAN (4-299): 3.07e-63: 205: 19.68		ERD21_HUMAN (1-212): 1.2e-82: 246: 100.00
+	Hs
		664950 P2RY2_HUMAN (2-281): 1.84e-62: 203: 21.55		ERD21_HUMAN (1-212): 1.2e-82: 246: 100.00
+	Hs
		225364 LPAR6_HUMAN (6-280): 1.58e-60: 197: 19.18		ERD23_HUMAN (1-211): 1.51e-83: 248: 72.99
+	Hs
		664963 PAR2_HUMAN (2-280): 3.28e-56: 188: 20.91		ERD21_HUMAN (1-212): 1.2e-82: 246: 100.00