HitPredict

Interactor 1: BET1 (O15155)
BET1 homolog (hBET1) (Golgi vesicular membrane-trafficking protein p18)
Gene: BET1

Interactor 2: VAMP8 (Q9BV40)
Vesicle-associated membrane protein 8 (VAMP-8) (Endobrevin) (EDB)
Gene: VAMP8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	29568061, 33961781, unassigned1655
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0015031 - protein transport GO:0016020 - membrane GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 118 Hs			1 100
+	Hs
		169416 BET1_HUMAN (1-118): 1.93e-45: 144: 100.00		VAMP7_HUMAN (1-100): 1.25e-26: 99.2: 38.00
+	Hs
		169474 BET1_HUMAN (1-118): 1.93e-45: 144: 100.00		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Rn
		1125559 BET1_RAT (1-118): 6.04e-46: 145: 93.22		YKT6_RAT (1-64): 7.61e-22: 86.1: 29.69
+	Dm
		1178137 Q9VVX6_DROME (11-118): 1.25e-27: 99.6: 39.45		Q7JYX5_DROME (1-100): 8.7e-32: 112: 32.00
+	Dm
		577258 Q9VVX6_DROME (11-118): 1.25e-27: 99.6: 39.45		SYB_DROME (5-95): 3.25e-30: 106: 27.47
+	Dm
		577224 Q7JRF1_DROME (9-111): 2.25e-24: 96.2: 20.91		SYB_DROME (5-95): 3.25e-30: 106: 27.47
+	Sc
		611769 BET1_YEAST (13-114): 6.27e-25: 93.5: 22.12		SNC2_YEAST (5-81): 2.16e-25: 93: 24.68
+	Sc
		611796 BET1_YEAST (13-114): 6.27e-25: 93.5: 22.12		NYV1_YEAST (3-99): 2.82e-22: 88.4: 24.75
+	Hs
		212772 STX6_HUMAN (10-97): 1.23e-19: 82.3: 19.32		VAMP7_HUMAN (1-100): 1.25e-26: 99.2: 38.00
+	Rn
		1144363 STX6_RAT (10-97): 1.99e-20: 84.6: 19.32		VAMP1_RAT (6-85): 9.7e-27: 96.5: 33.75
+	Hs
		235129 STX10_HUMAN (12-97): 4.1e-20: 83.5: 15.12		VAMP4_HUMAN (7-80): 3.4e-25: 93.4: 29.73
+	Hs
		1079455 BET1L_HUMAN (26-115): 3.07e-22: 85.8: 35.87		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		212689 STX6_HUMAN (10-97): 1.23e-19: 82.3: 19.32		VAMP4_HUMAN (7-80): 3.4e-25: 93.4: 29.73
+	Hs
		235174 STX10_HUMAN (12-97): 4.1e-20: 83.5: 15.12		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		212844 STX6_HUMAN (10-97): 1.23e-19: 82.3: 19.32		VAMP3_HUMAN (7-79): 2.36e-24: 89.9: 36.99
+	Hs
		212988 STX6_HUMAN (10-97): 1.23e-19: 82.3: 19.32		VAMP8_HUMAN (1-100): 2.94e-24: 89.6: 100.00
+	Rn
		192329 BET1L_RAT (26-114): 9.01e-22: 84.6: 36.26		YKT6_RAT (1-64): 7.61e-22: 86.1: 29.69
+	Hs
		212790 STX6_HUMAN (10-97): 1.23e-19: 82.3: 19.32		VAMP2_HUMAN (6-82): 2.47e-23: 88: 35.07
+	Rn
		1144365 STX6_RAT (10-97): 1.99e-20: 84.6: 19.32		VAMP8_RAT (3-76): 1.6e-22: 85.3: 94.60
+	Hs
		87583 STX8_HUMAN (6-99): 1.08e-09: 55.7: 17.02		C9JXZ5_HUMAN (27-100): 3.6e-20: 78.5: 100.00