Interactor 1: CTDSL (O15194)
CTD small phosphatase-like protein (CTDSP-like) (EC 3.1.3.16) (Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3) (NIF-like protein) (Nuclear LIM interactor-interacting factor 1) (NLI-interacting factor 1) (Protein YA22) (hYA22) (RBSP3) (Small C-terminal domain phosphatase 3) (SCP3) (Small CTD phosphatase 3)
Gene: CTDSPL

Interactor 2: CTDS1 (Q9GZU7)
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 3) (NLI-IF) (NLI-interacting factor 3) (Small C-terminal domain phosphatase 1) (SCP1) (Small CTD phosphatase 1)
Gene: CTDSP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains NIF~NIF
Common GO terms GO:0001933 - negative regulation of protein phosphorylation
GO:0005634 - nucleus
GO:0008420 - RNA polymerase II CTD heptapeptide repeat phosphatase activity
GO:0017018 - myosin phosphatase activity
GO:0046872 - metal ion binding
and 2 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 276
Hs

1 261
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024