Interactor 1: ARHGA (O15013)
Rho guanine nucleotide exchange factor 10
Gene: ARHGEF10
Interactor 2: ARGAL (Q9HCE6)
Rho guanine nucleotide exchange factor 10-like protein (GrinchGEF)
Gene: ARHGEF10L
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.70 | 1.00 | 0.839 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32203420, 33961781, unassigned2213 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | RhoGEF~RhoGEF, WD40_2~WD40_2 |
| Common GO terms | GO:0005085 - guanyl-nucleotide exchange factor activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030036 - actin cytoskeleton organization GO:0051056 - regulation of small GTPase mediated signal transduction and 1 others more... |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
