HitPredict

Interactor 1: CE290 (O15078)
Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)
Gene: CEP290

Interactor 2: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28007913
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2479 Hs			1 870
+	Hs
		176966 CE290_HUMAN (1-2479): 0: 663: 100.00		DYST_HUMAN (457-866): 1.24e-66: 245: 12.07
+	Hs
		942599 GOGA4_HUMAN (1674-2476): 5.7e-23: 110: 11.21		BCAR1_HUMAN (1-870): 1.95e-107: 353: 100.00
+	Hs
		942960 MACF1_HUMAN (859-2479): 1.53e-20: 102: 9.70		BCAR1_HUMAN (1-870): 1.95e-107: 353: 100.00
+	Hs
		776790 MYH11_HUMAN (1732-2478): 5.31e-17: 90.6: 15.76		BCAR1_HUMAN (1-870): 1.95e-107: 353: 100.00
+	Hs
		1143304 PLEC_HUMAN (2-1203): 2.95e-36: 154: 9.37		MACF1_HUMAN (505-867): 2.95e-74: 268: 13.79
+	Hs
		772800 MYH9_HUMAN (1711-2478): 3.16e-20: 101: 15.34		CASL_HUMAN (1-868): 5.72e-90: 305: 35.85
+	Hs
		1040296 PLEC_HUMAN (2-1203): 2.95e-36: 154: 9.37		DYST_HUMAN (457-866): 1.24e-66: 245: 12.07
+	Mm
		204405 MY18A_MOUSE (214-910): 1.2e-12: 76.4: 16.98		CASL_MOUSE (1-868): 7.79e-92: 310: 36.68
+	Hs
		1040365 CP250_HUMAN (6-974): 1.05e-31: 139: 10.65		DYST_HUMAN (457-866): 1.24e-66: 245: 12.07
+	Hs
		1462480 MACF1_HUMAN (859-2479): 1.53e-20: 102: 9.70		MACF1_HUMAN (505-867): 2.95e-74: 268: 13.79
+	Hs
		773085 MYH9_HUMAN (1711-2478): 3.16e-20: 101: 15.34		MACF1_HUMAN (505-867): 2.95e-74: 268: 13.79
+	Hs
		1040405 MACF1_HUMAN (859-2479): 1.53e-20: 102: 9.70		DYST_HUMAN (457-866): 1.24e-66: 245: 12.07
+	Hs
		772753 MYH9_HUMAN (1711-2478): 3.16e-20: 101: 15.34		DYST_HUMAN (457-866): 1.24e-66: 245: 12.07
+	Hs
		1035528 CENPE_HUMAN (5-1551): 1.56e-52: 207: 10.96		TITIN_HUMAN (56-404): 7.29e-09: 62.1: 14.93
+	Hs
		116295 MYH9_HUMAN (1711-2478): 3.16e-20: 101: 15.34		H3BPE1_HUMAN (459-867): 4.03e-36: 150: 12.86
+	Mm
		236901 MYH10_MOUSE (1471-2471): 7.33e-27: 122: 12.61		ACK1_MOUSE (9-581): 2.89e-29: 127: 13.93
+	Hs
		1143196 PLEC_HUMAN (2-1203): 2.95e-36: 154: 9.37		KMT2C_HUMAN (103-742): 7.2e-12: 71.8: 10.09
+	Mm
		236938 MY18A_MOUSE (214-910): 1.2e-12: 76.4: 16.98		ACK1_MOUSE (9-581): 2.89e-29: 127: 13.93
+	Hs
		772931 MYH9_HUMAN (1711-2478): 3.16e-20: 101: 15.34		TITIN_HUMAN (56-404): 7.29e-09: 62.1: 14.93
+	Hs
		587751 DESP_HUMAN (260-1441): 1.72e-12: 76: 15.78		TITIN_HUMAN (56-404): 7.29e-09: 62.1: 14.93