Interactor 1: TMPS2 (O15393)
Transmembrane protease serine 2 (EC 3.4.21.122) (Serine protease 10) [Cleaved into: Transmembrane protease serine 2 non-catalytic chain; Transmembrane protease serine 2 catalytic chain]
Gene: TMPRSS2
Interactor 2: MEGF8 (Q7Z7M0)
Multiple epidermal growth factor-like domains protein 8 (Multiple EGF-like domains protein 8) (Epidermal growth factor-like protein 4) (EGF-like protein 4)
Gene: MEGF8
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 34709727 |
| Identification Methods | proximity labelling technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CUB~Trypsin |
| Common GO terms | GO:0070062 - extracellular exosome |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025