HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: EF1A2 (Q05639)
Elongation factor 1-alpha 2 (EF-1-alpha-2) (Eukaryotic elongation factor 1 A-2) (eEF1A-2) (Statin-S1)
Gene: EEF1A2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35256949, 24244333
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0019901 - protein kinase binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 463
+	Hs
		227130 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		EF1A1_HUMAN (1-462): 0: 558: 92.42
+	Hs
		226427 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ERF3A_HUMAN (2-444): 1.97e-157: 457: 36.26
+	Hs
		228009 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		ERF3B_HUMAN (2-444): 3.45e-155: 456: 35.81
+	Hs
		229149 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		HBS1L_HUMAN (5-443): 1.08e-150: 446: 38.95
+	Hs
		312566 ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82		EF1A1_HUMAN (1-462): 0: 558: 92.42
+	Sc
		367642 UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72		EF1A_YEAST (1-443): 0: 523: 80.14
+	Xl
		568008 Q7SY79_XENLA (1-149): 2.25e-49: 179: 19.33		EF1A2_XENLA (1-461): 0: 548: 89.15
+	Hs
		1377778 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		HBS1L_HUMAN (5-443): 1.08e-150: 446: 38.95
+	Hs
		475654 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		EF1A2_HUMAN (1-463): 0: 560: 100.00
+	At
		1012702 UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17		EF1A3_ARATH (1-461): 1.71e-179: 511: 74.40
+	Zm
		24723 A0A1D6IJX7_MAIZE (233-459): 1.19e-26: 116: 21.70		B6UHJ4_MAIZE (1-448): 1.67e-176: 503: 77.01
+	Zm
		24695 A0A1D6IJX7_MAIZE (233-459): 1.19e-26: 116: 21.70		A0A1D6M1G2_MAIZE (1-448): 4.03e-175: 500: 75.66
+	Hs
		476620 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		HBS1L_HUMAN (5-443): 1.08e-150: 446: 38.95