HitPredict

Interactor 1: K1C19 (P08727)
Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)
Gene: KRT19

Interactor 2: K2C7 (P08729)
Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin) (Type-II keratin Kb7)
Gene: KRT7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005829 - cytosol GO:0005882 - intermediate filament GO:0045109 - intermediate filament organization GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 400 Hs			1 469
+	Hs
		437062 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28
+	Hs
		475561 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K22O_HUMAN (63-419): 5.29e-158: 463: 66.48
+	Hs
		475506 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C3_HUMAN (63-406): 3.22e-139: 415: 67.72
+	Hs
		475701 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		KRT84_HUMAN (11-453): 3.66e-103: 321: 57.43
+	Hs
		475559 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		KRT83_HUMAN (2-438): 1.11e-101: 314: 50.57
+	Hs
		475576 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		KRT81_HUMAN (2-438): 1.25e-100: 312: 50.57
+	Hs
		227200 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		KRT86_HUMAN (2-451): 3.39e-100: 310: 49.34
+	Hs
		475560 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		KRT85_HUMAN (12-455): 3.36e-96: 300: 51.69
+	Hs
		475621 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C73_HUMAN (4-406): 6.93e-94: 295: 58.50
+	Hs
		341726 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C75_HUMAN (3-417): 2.29e-89: 284: 61.59
+	Hs
		475598 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C79_HUMAN (7-421): 5.86e-88: 280: 57.58
+	Hs
		475702 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		KRT82_HUMAN (1-421): 2.32e-88: 280: 53.07
+	Hs
		475588 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C71_HUMAN (3-461): 9.68e-83: 266: 52.58
+	Hs
		475579 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C72_HUMAN (7-468): 4.88e-82: 264: 54.00
+	Hs
		407240 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C6B_HUMAN (56-426): 1.23e-78: 257: 69.89
+	Hs
		475542 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C6C_HUMAN (56-462): 1.27e-78: 257: 64.71
+	Hs
		385220 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C6A_HUMAN (56-462): 2.37e-77: 253: 65.44
+	Hs
		475510 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C5_HUMAN (56-413): 7.41e-77: 252: 71.87
+	Hs
		475613 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C74_HUMAN (29-467): 3.66e-76: 249: 52.50
+	Hs
		475516 K1C19_HUMAN (1-400): 2.56e-156: 448: 100.00		K2C4_HUMAN (55-422): 6.52e-69: 230: 65.31