HitPredict

Interactor 1: K2C7 (P08729)
Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin) (Type-II keratin Kb7)
Gene: KRT7

Interactor 2: K1C15 (P19012)
Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)
Gene: KRT15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005882 - intermediate filament GO:0045109 - intermediate filament organization GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 469 Hs			1 456
+	Hs
		437064 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		K1C16_HUMAN (101-418): 1.74e-155: 451: 76.10
+	Hs
		437088 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		K1C15_HUMAN (1-456): 3.49e-155: 449: 100.00
+	Hs
		385035 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		K1C14_HUMAN (103-454): 5.37e-146: 426: 69.58
+	Hs
		437152 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		K1C17_HUMAN (98-454): 4.41e-140: 410: 68.91
+	Hs
		437062 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		K1C19_HUMAN (59-414): 3.73e-140: 409: 64.89
+	Hs
		437075 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		K1C10_HUMAN (100-411): 1.17e-129: 389: 66.56
+	Hs
		437183 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		K1H1_HUMAN (99-417): 4.49e-126: 374: 57.81
+	Hs
		300259 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		KT33A_HUMAN (99-417): 5.56e-123: 365: 57.68
+	Hs
		437171 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		KT33B_HUMAN (99-417): 1.86e-122: 364: 57.19
+	Hs
		300282 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		KRT34_HUMAN (99-417): 5.48e-120: 357: 56.56
+	Hs
		227198 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		KRT86_HUMAN (4-417): 6.61e-95: 296: 23.86
+	Hs
		341724 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		K2C75_HUMAN (2-428): 1.15e-93: 295: 24.05
+	Hs
		437198 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		K2C71_HUMAN (4-420): 5.17e-85: 272: 24.36
+	Hs
		437176 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		K2C72_HUMAN (21-420): 1.78e-82: 265: 25.31
+	Hs
		300545 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		KRT36_HUMAN (6-454): 1.12e-78: 253: 48.61
+	Hs
		437172 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		K1H2_HUMAN (1-426): 2.82e-78: 252: 47.18
+	Hs
		407237 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		K2C6B_HUMAN (70-435): 1.51e-76: 251: 23.98
+	Hs
		437077 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		K2C5_HUMAN (70-420): 2.45e-76: 251: 25.57
+	Hs
		437121 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		K2C6C_HUMAN (70-435): 2.65e-76: 250: 23.98
+	Hs
		385216 K2C8_HUMAN (1-439): 8.81e-161: 465: 61.28		K2C6A_HUMAN (70-435): 2.36e-75: 247: 24.25