HitPredict

Interactor 1: ACK1 (O54967)
Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2)
Gene: Tnk2

Interactor 2: LCP2 (Q60787)
Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76)
Gene: LCP2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	28188290
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1055 Mm			1 533
+	Hs
		1060772 ACK1_HUMAN (1-1055): 0: 823: 92.89		LCP2_HUMAN (1-531): 2.4e-76: 252: 80.98
+	Mm
		813521 FYN_MOUSE (1-400): 7.78e-129: 404: 30.94		LCP2_MOUSE (1-533): 2.26e-78: 257: 100.00
+	Hs
		440526 FYN_HUMAN (1-400): 5.16e-129: 404: 30.94		LCP2_HUMAN (1-531): 2.4e-76: 252: 80.98
+	Hs
		557270 SRC_HUMAN (1-400): 1.61e-128: 403: 31.42		LCP2_HUMAN (1-531): 2.4e-76: 252: 80.98
+	Hs
		440054 LCK_HUMAN (1-400): 5.72e-127: 398: 30.18		LCP2_HUMAN (1-531): 2.4e-76: 252: 80.98
+	Hs
		473410 HCK_HUMAN (1-397): 1.05e-123: 390: 29.90		LCP2_HUMAN (1-531): 2.4e-76: 252: 80.98
+	Mm
		813537 FYN_MOUSE (1-400): 7.78e-129: 404: 30.94		CLNK_MOUSE (170-528): 4.91e-36: 141: 25.20
+	Hs
		1051009 FAK1_HUMAN (6-718): 8.35e-130: 422: 21.16		TENS3_HUMAN (52-512): 2.05e-27: 119: 12.63
+	Mm
		571269 FGR_MOUSE (1-401): 3.45e-127: 398: 30.85		CLNK_MOUSE (170-528): 4.91e-36: 141: 25.20
+	Hs
		362149 ABL1_HUMAN (2-994): 1.48e-147: 471: 19.88		MUC1_HUMAN (130-443): 7.13e-11: 67.1: 12.58
+	Hs
		215893 LCK_HUMAN (1-400): 5.72e-127: 398: 30.18		SYNJ1_HUMAN (10-467): 3.19e-32: 134: 10.96
+	Hs
		557345 SRC_HUMAN (1-400): 1.61e-128: 403: 31.42		TENS3_HUMAN (52-512): 2.05e-27: 119: 12.63
+	Hs
		932087 EPHA4_HUMAN (74-487): 5.17e-123: 402: 24.82		TENS3_HUMAN (52-512): 2.05e-27: 119: 12.63
+	Hs
		440737 FYN_HUMAN (1-400): 5.16e-129: 404: 30.94		TENS1_HUMAN (65-512): 1.71e-21: 100: 13.11
+	Hs
		440144 LCK_HUMAN (1-400): 5.72e-127: 398: 30.18		MINK1_HUMAN (115-430): 3.96e-22: 102: 14.11
+	Mm
		683114 LYN_MOUSE (85-387): 1.54e-107: 347: 36.39		CLNK_MOUSE (170-528): 4.91e-36: 141: 25.20
+	Hs
		557066 SRC_HUMAN (1-400): 1.61e-128: 403: 31.42		MUC1_HUMAN (130-443): 7.13e-11: 67.1: 12.58
+	Hs
		440773 FYN_HUMAN (1-400): 5.16e-129: 404: 30.94		MAGL2_HUMAN (56-440): 2.87e-09: 62.1: 7.79
+	Hs
		440738 FYN_HUMAN (1-400): 5.16e-129: 404: 30.94		MAGE1_HUMAN (125-441): 3.83e-09: 61.7: 12.38
+	Hs
		439935 LCK_HUMAN (1-400): 5.72e-127: 398: 30.18		MUC1_HUMAN (130-443): 7.13e-11: 67.1: 12.58