HitPredict

Interactor 1: CC14B (O60729)
Dual specificity protein phosphatase CDC14B (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog B)
Gene: CDC14B

Interactor 2: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	24412244
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 498 Hs			1 156
+	Hs
		239422 CC14B_HUMAN (1-498): 0: 593: 100.00		ANR50_HUMAN (26-149): 1.07e-26: 106: 26.61
+	Hs
		239362 CC14B_HUMAN (1-498): 0: 593: 100.00		ANR44_HUMAN (2-76): 4.04e-10: 58.8: 18.99
+	Hs
		166860 CC14B_HUMAN (1-498): 0: 593: 100.00		ANR28_HUMAN (82-155): 3.69e-09: 56.1: 16.22
+	Hs
		260528 TP4A3_HUMAN (235-361): 5.66e-40: 144: 27.82		CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00
+	Hs
		1219833 DUS16_HUMAN (181-493): 1.08e-61: 215: 16.87		ANKH1_HUMAN (68-155): 3.32e-18: 82.3: 19.32
+	Hs
		474837 SSH1_HUMAN (206-464): 1.29e-53: 196: 13.11		POTEI_HUMAN (49-152): 1.58e-18: 83.1: 13.89
+	Hs
		60258 TP4A3_HUMAN (235-361): 5.66e-40: 144: 27.82		POTEF_HUMAN (1-130): 1.26e-29: 115: 19.55
+	Hs
		161735 GAK_HUMAN (153-455): 1.96e-44: 169: 13.51		KDIS_HUMAN (86-156): 1.81e-12: 65.8: 19.48
+	Hs
		257617 DUS5_HUMAN (233-433): 9.77e-40: 149: 17.07		ANR17_HUMAN (69-147): 2.99e-19: 85.1: 20.25
+	Hs
		1086149 DUS5_HUMAN (233-433): 9.77e-40: 149: 17.07		ANKH1_HUMAN (68-155): 3.32e-18: 82.3: 19.32
+	Hs
		276177 DUS8_HUMAN (181-487): 5.52e-43: 163: 13.40		PSD10_HUMAN (1-85): 4.57e-12: 63.1: 23.86
+	Hs
		474845 DUS23_HUMAN (215-365): 8.14e-37: 134: 28.21		POTEI_HUMAN (49-152): 1.58e-18: 83.1: 13.89
+	Hs
		56494 PTPC1_HUMAN (200-434): 6.73e-41: 158: 24.42		ANR28_HUMAN (82-155): 3.69e-09: 56.1: 16.22
+	Hs
		310043 PTEN_HUMAN (190-380): 4.53e-37: 142: 20.30		TNKS1_HUMAN (49-142): 1.94e-13: 68.6: 25.26
+	Hs
		167013 DUS15_HUMAN (230-465): 2.65e-42: 154: 10.79		ANR28_HUMAN (82-155): 3.69e-09: 56.1: 16.22
+	Hs
		260624 TP4A3_HUMAN (235-361): 5.66e-40: 144: 27.82		RAI14_HUMAN (1-64): 1.97e-11: 62.7: 21.21
+	Hs
		890841 PTEN_HUMAN (190-380): 4.53e-37: 142: 20.30		TNKS2_HUMAN (8-136): 1.5e-11: 63.2: 21.05
+	Hs
		1264017 DUS23_HUMAN (215-365): 8.14e-37: 134: 28.21		ASB13_HUMAN (80-147): 2.84e-11: 61.6: 23.53