Interactor 1: TLR2 (O60603)
Toll-like receptor 2 (Toll/interleukin-1 receptor-like protein 4) (CD antigen CD282)
Gene: TLR2

Interactor 2: IRF3 (Q14653)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 17126870
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0032728 - positive regulation of interferon-beta production
and 4 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 784
Hs

1 427
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Last updated: 11Aug2025