HitPredict

Interactor 1: PIAS1 (O75925)
E3 SUMO-protein ligase PIAS1 (EC 2.3.2.-) (DEAD/H box-binding protein 1) (E3 SUMO-protein transferase PIAS1) (Gu-binding protein) (GBP) (Protein inhibitor of activated STAT protein 1) (RNA helicase II-binding protein)
Gene: PIAS1

Interactor 2: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	18157088
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008270 - zinc ion binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 651 Hs			1 548
+	Hs
		278144 PIAS1_HUMAN (1-651): 0: 874: 100.00		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		1317554 PIAS3_HUMAN (1-651): 0: 740: 56.88		TRI55_HUMAN (1-548): 6.44e-121: 368: 100.00
+	Hs
		278162 PIAS1_HUMAN (1-651): 0: 874: 100.00		TRIM5_HUMAN (13-396): 3.08e-68: 230: 14.32
+	Hs
		277914 PIAS1_HUMAN (1-651): 0: 874: 100.00		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		278333 PIAS2_HUMAN (1-566): 0: 633: 58.97		TRI55_HUMAN (1-548): 6.44e-121: 368: 100.00
+	Hs
		1282085 PIAS3_HUMAN (1-651): 0: 740: 56.88		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		1318360 PIAS3_HUMAN (1-651): 0: 740: 56.88		TRIM8_HUMAN (18-465): 8.09e-65: 222: 18.25
+	Hs
		537154 PIAS3_HUMAN (1-651): 0: 740: 56.88		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		278315 PIAS2_HUMAN (1-566): 0: 633: 58.97		TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30
+	Hs
		278217 PIAS2_HUMAN (1-566): 0: 633: 58.97		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		536921 PIAS4_HUMAN (2-423): 0: 550: 51.42		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		278295 PIAS2_HUMAN (1-566): 0: 633: 58.97		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		1030009 ZMIZ1_HUMAN (65-441): 7.58e-76: 264: 20.21		TIF1B_HUMAN (18-534): 7.29e-67: 233: 15.37
+	Hs
		1170889 ZMIZ2_HUMAN (64-423): 3.94e-88: 296: 23.04		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39
+	Hs
		1172236 ZMIZ1_HUMAN (65-441): 7.58e-76: 264: 20.21		TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39