HitPredict

Interactor 1: TACC1 (O75410)
Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1)
Gene: TACC1

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	35384245, 34273398
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 805 Hs			1 1620
+	Hs
		1437144 UBP42_HUMAN (37-578): 4.09e-36: 149: 10.20		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		215959 SYNJ1_HUMAN (250-637): 1.55e-11: 70.4: 9.32		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		280987 TACC1_HUMAN (1-805): 1.58e-108: 352: 100.00		RET_HUMAN (804-1477): 5.87e-139: 460: 23.15
+	Hs
		179586 TACC1_HUMAN (1-805): 1.58e-108: 352: 100.00		MUSK_HUMAN (983-1391): 1.78e-119: 399: 29.98
+	Hs
		280990 TACC1_HUMAN (1-805): 1.58e-108: 352: 100.00		ROS1_HUMAN (1039-1461): 3.97e-112: 397: 37.75
+	Hs
		280986 TACC1_HUMAN (1-805): 1.58e-108: 352: 100.00		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		280988 TACC1_HUMAN (1-805): 1.58e-108: 352: 100.00		IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77
+	Hs
		334271 TACC2_HUMAN (38-804): 5.76e-50: 193: 26.33		RET_HUMAN (804-1477): 5.87e-139: 460: 23.15
+	Hs
		280995 TACC1_HUMAN (1-805): 1.58e-108: 352: 100.00		INSRR_HUMAN (1082-1384): 2.39e-70: 262: 43.46
+	Hs
		281049 TACC1_HUMAN (1-805): 1.58e-108: 352: 100.00		NTRK3_HUMAN (1093-1375): 2.7e-59: 223: 39.03
+	Hs
		280993 TACC1_HUMAN (1-805): 1.58e-108: 352: 100.00		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07
+	Rn
		92923 D3ZGN7_RAT (4-789): 3.1e-42: 169: 11.70		INSR_RAT (973-1484): 1.46e-112: 392: 32.38
+	Hs
		590283 MUC1_HUMAN (3-588): 8.52e-35: 145: 10.37		ERBB4_HUMAN (882-1541): 4.43e-121: 415: 22.42
+	Hs
		1145741 TENS2_HUMAN (26-394): 6.28e-30: 130: 13.25		ERBB4_HUMAN (882-1541): 4.43e-121: 415: 22.42
+	Hs
		412901 TACC3_HUMAN (56-803): 5.31e-46: 179: 22.54		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		412177 HUWE1_HUMAN (166-500): 1.87e-23: 109: 12.30		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		541547 TENS2_HUMAN (26-394): 6.28e-30: 130: 13.25		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07
+	Hs
		541564 MICA3_HUMAN (2-777): 1.48e-21: 103: 10.80		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07
+	Hs
		215899 SYNJ1_HUMAN (250-637): 1.55e-11: 70.4: 9.32		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07