HitPredict

Interactor 1: TAF5L (O75529)
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (TAF5L) (PCAF-associated factor 65 beta) (PAF65-beta)
Gene: TAF5L

Interactor 2: MAX (P61244)
Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)
Gene: MAX

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12660246
Identification Methods	coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 589 Hs			1 160
+	Hs
		959629 FBXW7_HUMAN (299-588): 6.08e-72: 246: 21.05		MAX_HUMAN (1-160): 2.06e-31: 112: 100.00
+	Mm
		1189859 FBXW7_MOUSE (299-588): 9.47e-70: 240: 23.02		SRBP2_MOUSE (19-149): 2.22e-30: 117: 26.32
+	Hs
		371397 LIS1_HUMAN (86-498): 2.18e-80: 260: 14.32		MYC_HUMAN (14-105): 1.82e-21: 91.5: 34.74
+	Hs
		787890 FBXW7_HUMAN (299-588): 6.08e-72: 246: 21.05		SRBP1_HUMAN (9-149): 2.93e-25: 102: 20.00
+	Mm
		1353851 FBXW7_MOUSE (299-588): 9.47e-70: 240: 23.02		SRBP1_MOUSE (9-134): 2.96e-25: 102: 19.38
+	Hs
		372767 FBXW7_HUMAN (299-588): 6.08e-72: 246: 21.05		MYC_HUMAN (14-105): 1.82e-21: 91.5: 34.74
+	Hs
		406466 FBXW7_HUMAN (299-588): 6.08e-72: 246: 21.05		MYCN_HUMAN (7-101): 2.1e-21: 91.1: 33.67
+	Mm
		373704 FBXW7_MOUSE (299-588): 9.47e-70: 240: 23.02		MYC_MOUSE (19-105): 1.04e-21: 91.9: 37.50
+	Hs
		373290 NLE1_HUMAN (333-588): 1.96e-70: 236: 21.71		MYC_HUMAN (14-105): 1.82e-21: 91.5: 34.74
+	Hs
		284922 TAF5L_HUMAN (388-588): 3.54e-43: 164: 22.32		MYOD1_HUMAN (11-151): 1.24e-24: 98.4: 16.33
+	Hs
		284911 TAF5L_HUMAN (388-588): 3.54e-43: 164: 22.32		MYC_HUMAN (14-105): 1.82e-21: 91.5: 34.74
+	Hs
		284921 TAF5L_HUMAN (388-588): 3.54e-43: 164: 22.32		MYCL_HUMAN (7-104): 3.79e-20: 86.9: 30.77
+	Hs
		372801 SNR40_HUMAN (418-588): 7.79e-40: 150: 26.59		MYC_HUMAN (14-105): 1.82e-21: 91.5: 34.74
+	Hs
		406479 SNR40_HUMAN (418-588): 7.79e-40: 150: 26.59		MYCN_HUMAN (7-101): 2.1e-21: 91.1: 33.67
+	Hs
		261363 TBL1X_HUMAN (141-373): 4.1e-22: 102: 10.37		MYOD1_HUMAN (11-151): 1.24e-24: 98.4: 16.33
+	Mm
		704106 WDR5_MOUSE (498-588): 8.85e-16: 80.9: 20.88		MAX_MOUSE (1-160): 4.62e-32: 113: 99.38
+	Hs
		959549 WDR5_HUMAN (498-588): 8.85e-16: 80.9: 20.88		MAX_HUMAN (1-160): 2.06e-31: 112: 100.00
+	Hs
		648344 WDR5_HUMAN (498-588): 8.85e-16: 80.9: 20.88		USF1_HUMAN (10-115): 4.64e-23: 94.1: 30.97
+	Hs
		371643 WDR5_HUMAN (498-588): 8.85e-16: 80.9: 20.88		MYC_HUMAN (14-105): 1.82e-21: 91.5: 34.74
+	Hs
		405975 WDR5_HUMAN (498-588): 8.85e-16: 80.9: 20.88		MYCN_HUMAN (7-101): 2.1e-21: 91.1: 33.67