HitPredict

Interactor 1: PIAS1 (O75925)
E3 SUMO-protein ligase PIAS1 (EC 2.3.2.-) (DEAD/H box-binding protein 1) (E3 SUMO-protein transferase PIAS1) (Gu-binding protein) (GBP) (Protein inhibitor of activated STAT protein 1) (RNA helicase II-binding protein)
Gene: PIAS1

Interactor 2: ERG (P11308)
Transcriptional regulator ERG (Transforming protein ERG)
Gene: ERG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.614

The method score is based on:

Property Details
Experiments 35140242, 35914814
Identification Methods proximity labelling technology, two hybrid, two hybrid fragment pooling approach
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 651
Hs

1 479
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Service provided by Combinatics, Japan

Last updated: 11Aug2025