HitPredict

Interactor 1: TOX4 (O94842)
TOX high mobility group box family member 4 (Epidermal Langerhans cell protein LCP1)
Gene: TOX4

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 621 Hs			1 126
+	Hs
		1087463 HMGX4_HUMAN (55-335): 2.61e-40: 157: 20.41		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		918757 HMGX4_HUMAN (55-335): 2.61e-40: 157: 20.41		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		1087421 HM20A_HUMAN (133-423): 7.93e-36: 139: 16.56		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		918706 HM20A_HUMAN (133-423): 7.93e-36: 139: 16.56		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		707756 HM20A_HUMAN (133-423): 7.93e-36: 139: 16.56		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		420830 SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11		H2B1J_HUMAN (1-126): 7.8e-54: 166: 99.21
+	Hs
		918316 SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		996694 SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		996812 SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		643302 HMGB2_HUMAN (139-314): 2.31e-31: 123: 18.38		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		643380 HMGB2_HUMAN (139-314): 2.31e-31: 123: 18.38		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		643248 HMGB2_HUMAN (139-314): 2.31e-31: 123: 18.38		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		1282968 HM20A_HUMAN (133-423): 7.93e-36: 139: 16.56		H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04
+	Hs
		996768 SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11		H2B3B_HUMAN (1-126): 1.01e-51: 161: 96.03
+	Hs
		175767 HMGB3_HUMAN (150-309): 1.59e-29: 117: 20.96		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		449786 HMGB1_HUMAN (139-302): 5.39e-28: 113: 20.23		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		996816 SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11		H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04
+	Sc
		355756 NHP6B_YEAST (198-295): 3.26e-31: 118: 33.67		H2B2_YEAST (3-125): 4.73e-37: 124: 71.55
+	Sc
		355314 NHP6B_YEAST (198-295): 3.26e-31: 118: 33.67		H2B1_YEAST (3-125): 1.81e-36: 122: 71.55
+	Sc
		355313 NHP6A_YEAST (205-295): 3.25e-28: 110: 35.17		H2B1_YEAST (3-125): 1.81e-36: 122: 71.55