HitPredict

Interactor 1: FLOT1 (O75955)
Flotillin-1
Gene: FLOT1

Interactor 2: LMTK2 (Q8IWU2)
Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI-2)
Gene: LMTK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 1503
+	Hs
		1310882 STML2_HUMAN (8-217): 5.7e-13: 71.8: 18.48		LMTK2_HUMAN (1-1503): 0: 1229: 100.00
+	Hs
		299286 FLOT1_HUMAN (1-427): 3.28e-145: 421: 100.00		MINK1_HUMAN (113-1179): 5.17e-150: 494: 11.66
+	Hs
		641173 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		FGFR2_HUMAN (33-454): 3.18e-122: 404: 20.52
+	Hs
		931851 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		EPHA5_HUMAN (26-443): 1.15e-116: 395: 22.20
+	Hs
		541484 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		FGFR1_HUMAN (36-471): 4.94e-118: 393: 21.41
+	Hs
		299075 FLOT1_HUMAN (1-427): 3.28e-145: 421: 100.00		EPHA2_HUMAN (81-437): 3.66e-109: 372: 24.31
+	Hs
		710628 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		EPHA3_HUMAN (55-410): 1.12e-109: 374: 22.84
+	Hs
		710240 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		EPHA2_HUMAN (81-437): 3.66e-109: 372: 24.31
+	Hs
		932070 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		EPHA4_HUMAN (62-440): 4.24e-109: 372: 23.56
+	Hs
		463516 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		LYN_HUMAN (86-421): 3.37e-109: 358: 22.19
+	Hs
		1124821 FLOT2_HUMAN (4-419): 1.34e-139: 407: 47.61		NTRK2_HUMAN (119-410): 3.56e-37: 154: 33.99
+	Mm
		148497 FLOT1_MOUSE (1-427): 4.93e-143: 416: 98.13		INSR_MOUSE (131-407): 1.39e-32: 140: 33.57
+	Hs
		541748 STML2_HUMAN (8-217): 5.7e-13: 71.8: 18.48		FGFR1_HUMAN (36-471): 4.94e-118: 393: 21.41
+	Mm
		1041425 PODO_MOUSE (3-216): 3.25e-16: 81.8: 19.54		EPHA2_MOUSE (83-437): 9.54e-110: 374: 23.89
+	Hs
		412780 STML2_HUMAN (8-217): 5.7e-13: 71.8: 18.48		NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33
+	Mm
		1221441 PODO_MOUSE (3-216): 3.25e-16: 81.8: 19.54		IGF1R_MOUSE (131-399): 2.37e-32: 139: 31.90
+	Hs
		1034201 STML2_HUMAN (8-217): 5.7e-13: 71.8: 18.48		ROR1_HUMAN (112-404): 2.35e-29: 129: 28.57