Interactor 1: TRIO (O75962)
Triple functional domain protein (EC 2.7.11.1) (PTPRF-interacting protein)
Gene: TRIO
Interactor 2: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 34079125 |
| Identification Methods | proximity labelling technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PK_Tyr_Ser-Thr~Pkinase, RhoGEF~SH3_1, PK_Tyr_Ser-Thr~SH3_1, SH2~SH3_1, SH3_1~SH3_1, SH3_1~SOS1_NGEF_PH |
| Common GO terms | GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
