HitPredict

Interactor 1: SH21A (O88890)
SH2 domain-containing protein 1A (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP)
Gene: Sh2d1a

Interactor 2: KPCT (Q02111)
Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)
Gene: Prkcq

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20668219
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1_1~SH2
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 126 Mm			1 707
+	Hs
		440039 LCK_HUMAN (1-124): 9.23e-41: 143: 20.77		KPCT_HUMAN (1-706): 0: 826: 94.76
+	Hs
		440501 FYN_HUMAN (1-124): 8.26e-37: 132: 18.66		KPCT_HUMAN (1-706): 0: 826: 94.76
+	Hs
		440505 FYN_HUMAN (1-124): 8.26e-37: 132: 18.66		KPCD_HUMAN (1-705): 0: 773: 61.14
+	Hs
		557247 SRC_HUMAN (1-124): 9.34e-37: 132: 22.90		KPCD_HUMAN (1-705): 0: 773: 61.14
+	Hs
		1051952 SHIP1_HUMAN (6-126): 5.98e-34: 125: 38.84		KPCD_HUMAN (1-705): 0: 773: 61.14
+	Hs
		362255 ABL1_HUMAN (1-124): 5.9e-34: 125: 25.00		KPCD_HUMAN (1-705): 0: 773: 61.14
+	Mm
		440269 LCK_MOUSE (1-124): 1.29e-40: 142: 20.77		KPCE_MOUSE (21-696): 0: 692: 40.99
+	Mm
		431319 SRC_MOUSE (1-124): 9.55e-37: 132: 22.90		KPCE_MOUSE (21-696): 0: 692: 40.99
+	Hs
		440424 FYN_HUMAN (1-124): 8.26e-37: 132: 18.66		KPCI_HUMAN (57-703): 0: 547: 27.69
+	Hs
		557246 SRC_HUMAN (1-124): 9.34e-37: 132: 22.90		KPCZ_HUMAN (58-703): 1.27e-179: 526: 28.72
+	Hs
		362254 ABL1_HUMAN (1-124): 5.9e-34: 125: 25.00		KPCZ_HUMAN (58-703): 1.27e-179: 526: 28.72
+	Hs
		463366 LYN_HUMAN (1-124): 5.81e-39: 138: 19.23		AKT2_HUMAN (273-699): 7.04e-152: 451: 34.48
+	Hs
		440402 FYN_HUMAN (1-124): 8.26e-37: 132: 18.66		AKT1_HUMAN (320-700): 4.5e-151: 449: 40.26
+	Hs
		557128 SRC_HUMAN (1-124): 9.34e-37: 132: 22.90		AKT1_HUMAN (320-700): 4.5e-151: 449: 40.26
+	Mm
		431326 SRC_MOUSE (1-124): 9.55e-37: 132: 22.90		AKT1_MOUSE (278-700): 3.88e-149: 444: 36.57
+	Hs
		728082 CSK_HUMAN (1-124): 4.18e-35: 126: 25.00		AKT1_HUMAN (320-700): 4.5e-151: 449: 40.26
+	Dm
		1303724 Q9VGK8_DROME (1-104): 4.51e-24: 97.8: 27.89		AKT1_DROME (368-696): 1.72e-147: 444: 45.37
+	Hs
		436582 LYN_HUMAN (1-124): 5.81e-39: 138: 19.23		KPCB_HUMAN (133-385): 4.6e-42: 164: 29.55
+	Mm
		632514 GRB2_MOUSE (1-114): 1.36e-33: 118: 24.56		KPCA_MOUSE (131-406): 2.32e-42: 165: 27.93