HitPredict

Interactor 1: M4K4 (O95819)
Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (HPK/GCK-like kinase HGK) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (Nck-interacting kinase)
Gene: MAP4K4

Interactor 2: MOB1A (Q9H8S9)
MOB kinase activator 1A (Mob1 alpha) (Mob1A) (Mob1 homolog 1B) (Mps one binder kinase activator-like 1B)
Gene: MOB1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37536630
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1239 Hs			1 216
+	Hs
		324833 M4K4_HUMAN (1-1239): 0: 1227: 100.00		MOB1B_HUMAN (1-216): 5.52e-119: 338: 95.83
+	Hs
		324837 M4K4_HUMAN (1-1239): 0: 1227: 100.00		MOB3B_HUMAN (5-212): 2.16e-108: 311: 52.63
+	Hs
		324861 M4K4_HUMAN (1-1239): 0: 1227: 100.00		MOB3A_HUMAN (5-212): 2.62e-106: 306: 51.68
+	Hs
		324831 M4K4_HUMAN (1-1239): 0: 1227: 100.00		MOB3C_HUMAN (5-212): 7.65e-106: 305: 50.72
+	Hs
		324908 M4K4_HUMAN (1-1239): 0: 1227: 100.00		PHOCN_HUMAN (7-201): 8.64e-68: 209: 19.60
+	Hs
		1198329 MINK1_HUMAN (1-1239): 0: 1120: 59.29		MOB3B_HUMAN (5-212): 2.16e-108: 311: 52.63
+	Hs
		1174260 MINK1_HUMAN (1-1239): 0: 1120: 59.29		MOB3C_HUMAN (5-212): 7.65e-106: 305: 50.72
+	Hs
		1233571 MINK1_HUMAN (1-1239): 0: 1120: 59.29		PHOCN_HUMAN (7-201): 8.64e-68: 209: 19.60
+	Mm
		949324 TNIK_MOUSE (1-1239): 0: 1120: 62.43		PHOCN_MOUSE (7-201): 8.64e-68: 209: 19.60
+	Hs
		1356420 TNIK_HUMAN (1-1239): 0: 1101: 60.56		PHOCN_HUMAN (7-201): 8.64e-68: 209: 19.60
+	Hs
		1027437 STK3_HUMAN (4-499): 3.17e-119: 381: 30.60		MOB1A_HUMAN (1-216): 3.44e-119: 339: 100.00
+	Hs
		1027391 STK3_HUMAN (4-499): 3.17e-119: 381: 30.60		MOB1B_HUMAN (1-216): 5.52e-119: 338: 95.83
+	Hs
		1023117 STK4_HUMAN (4-517): 8.55e-119: 379: 31.92		MOB1A_HUMAN (1-216): 3.44e-119: 339: 100.00
+	Hs
		1023070 STK4_HUMAN (4-517): 8.55e-119: 379: 31.92		MOB1B_HUMAN (1-216): 5.52e-119: 338: 95.83
+	Hs
		1027394 STK3_HUMAN (4-499): 3.17e-119: 381: 30.60		MOB3B_HUMAN (5-212): 2.16e-108: 311: 52.63
+	Dm
		1178592 Q7KV89_DROME (3-813): 4.51e-117: 393: 40.32		MOB4_DROME (7-201): 2.56e-69: 212: 20.60
+	Hs
		1027459 STK3_HUMAN (4-499): 3.17e-119: 381: 30.60		PHOCN_HUMAN (7-201): 8.64e-68: 209: 19.60
+	Hs
		1023145 STK4_HUMAN (4-517): 8.55e-119: 379: 31.92		PHOCN_HUMAN (7-201): 8.64e-68: 209: 19.60
+	Dm
		1178607 Q9VEN3_DROME (20-340): 7.49e-112: 366: 42.72		MOB4_DROME (7-201): 2.56e-69: 212: 20.60
+	Hs
		131625 STK25_HUMAN (14-452): 5.34e-114: 364: 34.99		PHOCN_HUMAN (7-201): 8.64e-68: 209: 19.60