HitPredict

Interactor 1: TSN15 (O95858)
Tetraspanin-15 (Tspan-15) (Tetraspan NET-7) (Transmembrane 4 superfamily member 15)
Gene: TSPAN15

Interactor 2: AGTR1 (P30556)
Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1 receptor)
Gene: AGTR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 294 Hs			1 359
+	Hs
		326064 TSN15_HUMAN (1-294): 9.34e-96: 285: 100.00		GPR17_HUMAN (29-332): 8.43e-84: 260: 29.13
+	Hs
		208446 TSN15_HUMAN (1-294): 9.34e-96: 285: 100.00		OX2R_HUMAN (2-348): 1.9e-68: 223: 17.57
+	Hs
		326031 TSN15_HUMAN (1-294): 9.34e-96: 285: 100.00		NK3R_HUMAN (4-358): 3.43e-67: 220: 20.11
+	Hs
		326045 TSN15_HUMAN (1-294): 9.34e-96: 285: 100.00		CCR6_HUMAN (5-358): 6.24e-67: 217: 27.10
+	Hs
		783911 TSN7_HUMAN (7-265): 3.94e-67: 211: 23.85		CCR9_HUMAN (18-318): 1.49e-83: 259: 33.77
+	Hs
		502891 CD37_HUMAN (14-267): 2.18e-51: 172: 17.75		AGTR1_HUMAN (1-359): 5.59e-90: 276: 100.00
+	Hs
		428955 TSN7_HUMAN (7-265): 3.94e-67: 211: 23.85		ADRB2_HUMAN (8-341): 5.17e-74: 236: 20.11
+	Hs
		653086 CD82_HUMAN (13-264): 9.78e-57: 185: 17.80		BKRB2_HUMAN (15-323): 1.4e-80: 252: 31.73
+	Hs
		783809 TSN7_HUMAN (7-265): 3.94e-67: 211: 23.85		CCR2_HUMAN (5-327): 9.24e-70: 224: 29.70
+	Hs
		326039 TSN15_HUMAN (1-294): 9.34e-96: 285: 100.00		LPAR6_HUMAN (25-304): 2.66e-41: 149: 30.25
+	Hs
		849732 CD81_HUMAN (11-262): 1.8e-52: 173: 15.53		CCR9_HUMAN (18-318): 1.49e-83: 259: 33.77
+	Hs
		237805 TSN3_HUMAN (13-274): 3.38e-50: 167: 20.23		GPR17_HUMAN (29-332): 8.43e-84: 260: 29.13
+	Hs
		673752 CD81_HUMAN (11-262): 1.8e-52: 173: 15.53		BKRB2_HUMAN (15-323): 1.4e-80: 252: 31.73
+	Hs
		428918 CD9_HUMAN (11-263): 1.03e-52: 173: 15.33		ADRB2_HUMAN (8-341): 5.17e-74: 236: 20.11
+	Hs
		428997 CD81_HUMAN (11-262): 1.8e-52: 173: 15.53		ADRB2_HUMAN (8-341): 5.17e-74: 236: 20.11
+	Hs
		722930 CD81_HUMAN (11-262): 1.8e-52: 173: 15.53		ADA1A_HUMAN (7-351): 5.05e-69: 225: 18.30
+	Hs
		783813 CD81_HUMAN (11-262): 1.8e-52: 173: 15.53		CCR2_HUMAN (5-327): 9.24e-70: 224: 29.70
+	Hs
		237791 TSN3_HUMAN (13-274): 3.38e-50: 167: 20.23		OPRX_HUMAN (16-355): 6.5e-67: 217: 26.24
+	Hs
		237794 TSN3_HUMAN (13-274): 3.38e-50: 167: 20.23		CCR6_HUMAN (5-358): 6.24e-67: 217: 27.10
+	Hs
		446011 CD63_HUMAN (11-261): 4.27e-59: 190: 23.81		FPR2_HUMAN (37-353): 7.34e-41: 148: 30.89