HitPredict

Interactor 1: UBR5 (O95071)
E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein)
Gene: UBR5

Interactor 2: EGFL7 (Q9UHF1)
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)
Gene: EGFL7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2799 Hs			1 273
+	Dm
		263321 Q9W325_DROME (2355-2797): 3.12e-133: 427: 20.52		TENM_DROME (64-272): 2.73e-27: 112: 16.36
+	Dm
		263208 NEDD4_DROME (2436-2796): 4.31e-121: 412: 20.78		TENM_DROME (64-272): 2.73e-27: 112: 16.36
+	Hs
		1008021 ITCH_HUMAN (2187-2797): 8.98e-132: 440: 18.08		JAG1_HUMAN (66-168): 2.85e-10: 62.4: 28.57
+	Hs
		861610 NEDD4_HUMAN (2446-2796): 8.66e-120: 416: 23.98		FAT1_HUMAN (140-272): 1e-17: 84.9: 15.67
+	Mm
		1032088 ITCH_MOUSE (2187-2797): 1.89e-132: 441: 18.21		NOTC1_MOUSE (82-176): 3.28e-09: 59.4: 24.04
+	Hs
		857533 ITCH_HUMAN (2187-2797): 8.98e-132: 440: 18.08		NOTC1_HUMAN (85-183): 3.37e-09: 59.4: 21.57
+	Dm
		451975 SUDX_DROME (2189-2796): 5.34e-128: 431: 16.93		NOTCH_DROME (68-172): 2.45e-09: 59.8: 22.32
+	Hs
		857554 WWP1_HUMAN (2180-2797): 2.85e-126: 425: 18.43		NOTC1_HUMAN (85-183): 3.37e-09: 59.4: 21.57
+	Hs
		861657 NEDD4_HUMAN (2446-2796): 8.66e-120: 416: 23.98		FAT4_HUMAN (132-255): 2.96e-10: 62.5: 11.29
+	Hs
		861810 NEDD4_HUMAN (2446-2796): 8.66e-120: 416: 23.98		CELR1_HUMAN (28-182): 3.6e-10: 62.5: 17.65
+	Hs
		857539 NED4L_HUMAN (2187-2796): 1.96e-123: 418: 18.20		NOTC1_HUMAN (85-183): 3.37e-09: 59.4: 21.57
+	Hs
		861696 NEDD4_HUMAN (2446-2796): 8.66e-120: 416: 23.98		FAT3_HUMAN (21-134): 1.64e-09: 60.5: 17.89
+	Hs
		857371 NEDD4_HUMAN (2446-2796): 8.66e-120: 416: 23.98		NOTC1_HUMAN (85-183): 3.37e-09: 59.4: 21.57
+	Hs
		317575 HUWE1_HUMAN (2499-2798): 1.3e-100: 366: 27.27		SLIT2_HUMAN (59-271): 1.73e-25: 107: 12.29
+	Dm
		451922 NEDD4_DROME (2436-2796): 4.31e-121: 412: 20.78		NOTCH_DROME (68-172): 2.45e-09: 59.8: 22.32
+	Dm
		262945 SMUF1_DROME (2516-2792): 4.38e-20: 100: 27.34		TENM_DROME (64-272): 2.73e-27: 112: 16.36