Interactor 1: CO5 (P01031)
Complement C5 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4) [Cleaved into: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain]
Gene: C5
Interactor 2: CO8B (P07358)
Complement component C8 beta chain (Complement component 8 subunit beta)
Gene: C8B
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 3624872 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | A2M_BRD~Ldl_recept_a, MG1~TSP_1, NTR~TSP_1, MACPF~TED_complement, TED_complement~TSP_1 |
| Common GO terms | GO:0005576 - extracellular region GO:0005579 - membrane attack complex GO:0005615 - extracellular space GO:0006957 - complement activation, alternative pathway GO:0006958 - complement activation, classical pathway and 2 others more... |
| Homologous interactions | 5 |
Homologous interactions
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Last updated: 15 Jul 2024
