Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1
Interactor 2: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 0.60 | 0.765 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16957778, 22328528, 17043237, 27420286, 11013076, 17400812, 15020686, 12630920, 17627277, 11032808, 29720121, 11564893, 15784253, 14766010, 17284441, 17921256, 20935677, 24498420, 23065768, 14963108 |
| Identification Methods | pull down, two hybrid, affinity chromatography technology, fluorescent resonance energy transfer, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction and 5 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
