HitPredict

Interactor 1: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Interactor 2: HMGX4 (Q9UGU5)
HMG domain-containing protein 4 (HMG box-containing protein 4) (High mobility group protein 2-like 1) (Protein HMGBCG)
Gene: HMGXB4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 464 Hs			1 601
+	Hs
		379330 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		378934 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		HMGB1_HUMAN (388-485): 1.57e-24: 103: 30.00
+	Hs
		379037 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		HMGB2_HUMAN (405-494): 1.76e-22: 97.6: 35.56
+	Hs
		297442 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		TOX4_HUMAN (339-528): 4.7e-37: 148: 24.76
+	Hs
		347201 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		PB1_HUMAN (368-514): 1.71e-34: 142: 25.16
+	Hs
		346626 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		SSRP1_HUMAN (389-478): 6.97e-30: 126: 33.70
+	Hs
		346139 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		SOX3_HUMAN (403-551): 2.18e-29: 123: 19.46
+	Hs
		175737 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		HMGB3_HUMAN (411-495): 5.79e-12: 67.2: 21.84
+	Hs
		346609 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		SOX4_HUMAN (368-485): 7.99e-29: 121: 22.03
+	Hs
		345751 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		HMGB1_HUMAN (388-485): 1.57e-24: 103: 30.00
+	Hs
		345975 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		HMGB2_HUMAN (405-494): 1.76e-22: 97.6: 35.56
+	Hs
		252909 MITF_HUMAN (65-462): 8.44e-27: 114: 13.27		SOX2_HUMAN (377-551): 5.04e-32: 128: 16.57
+	Mm
		927934 SRBP1_MOUSE (91-464): 8.46e-31: 128: 16.80		HMGB1_MOUSE (388-485): 1.57e-24: 103: 30.00
+	Ce
		103982 MXL3_CAEEL (379-450): 1.78e-18: 86.3: 36.11		G5EBG6_CAEEL (324-542): 2.84e-35: 144: 16.86
+	Hs
		1300954 MLXPL_HUMAN (20-459): 2.62e-34: 138: 15.30		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29
+	Hs
		867119 SC24C_HUMAN (17-348): 1.44e-32: 133: 16.29		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29
+	Hs
		607835 USF1_HUMAN (184-463): 1.05e-29: 119: 17.83		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29
+	Hs
		1079724 USF2_HUMAN (199-463): 9.99e-26: 109: 17.34		CIC_HUMAN (362-527): 1.94e-12: 72.6: 25.29