HitPredict

Interactor 1: K2C6A (P02538)
Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK-6A) (Cytokeratin-6D) (CK-6D) (Keratin-6A) (K6A) (Type-II keratin Kb6) (allergen Hom s 5)
Gene: KRT6A

Interactor 2: K1C16 (P08779)
Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)
Gene: KRT16

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.843

The method score is based on:

Property Details
Experiments 35575683, 32296183, unassigned1304
Identification Methods cross-linking study, two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Filament~Filament
Common GO terms GO:0002009 - morphogenesis of an epithelium
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0031424 - keratinization
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 564
Hs

1 473
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025