HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: DDX50 (Q9BQ39)
ATP-dependent RNA helicase DDX50 (EC 3.6.4.13) (DEAD box protein 50) (Gu-beta) (Nucleolar protein Gu2)
Gene: DDX50

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 737
+	Hs
		418704 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		DDX21_HUMAN (20-736): 5.59e-143: 439: 59.86
+	Mm
		1143199 NPM_MOUSE (1-294): 7.04e-141: 400: 93.54		Q8BTS0_MOUSE (47-588): 1.09e-137: 420: 25.09
+	Hs
		133844 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		DDX3X_HUMAN (15-526): 5.63e-129: 399: 24.86
+	Hs
		271395 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		DDX50_HUMAN (1-737): 1.3e-174: 519: 100.00
+	Hs
		271427 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		DDX21_HUMAN (20-736): 5.59e-143: 439: 59.86