Protein: S1PR2
Sphingosine 1-phosphate receptor 2 (S1P receptor 2) (S1P2) (Endothelial differentiation G-protein coupled receptor 5) (Sphingosine 1-phosphate receptor Edg-5) (S1P receptor Edg-5)

Gene: S1PR2
Organism: Homo sapiens
Interactions: 30
UniProt ID: O95136

Gene Ontology (top 5):
GO:0001664 - G protein-coupled receptor binding
GO:0003376 - sphingosine-1-phosphate receptor signaling pathway
GO:0004930 - G protein-coupled receptor activity
GO:0005178 - integrin binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

326452

KC1G3
Casein kinase I isoform gamma-3

2

1

High-throughput

0.811

High

326439

WDFY1
WD repeat and FYVE domain-containing protein 1

2

3

High-throughput

0.726

High

326448

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

2

2

High-throughput

0.726

High

326436

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

20

High-throughput

0.691

High

326442

LPAR1
Lysophosphatidic acid receptor 1

1

17

High-throughput

0.691

High

125867

ARVC
Splicing regulator ARVCF

2

1

High-throughput

0.628

High

297123

PRAF3
PRA1 family protein 3

2

5

High-throughput

0.628

High

326427

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

2

6

High-throughput

0.628

High

326428

CO8G
Complement component C8 gamma chain

2

3

High-throughput

0.628

High

326429

LEG1
Galectin-1

2

5

High-throughput

0.628

High

326431

SRC
Proto-oncogene tyrosine-protein kinase Src

2

5

High-throughput

0.628

High

326441

NDRG1
Protein NDRG1

2

1

High-throughput

0.628

High

64684

PALM3
Paralemmin-3

2

0

High-throughput

0.602

High

326433

NEUM
Neuromodulin

2

0

High-throughput

0.602

High

326435

HPCL1
Hippocalcin-like protein 1

2

1

High-throughput

0.574

High

326426

TSN15
Tetraspanin-15

1

20

High-throughput

0.536

High

326446

TTYH1
Protein tweety homolog 1

1

11

High-throughput

0.536

High

326450

TNF18
Tumor necrosis factor ligand superfamily member 18

1

1

High-throughput

0.536

High

326451

ARL5A
ADP-ribosylation factor-like protein 5A

1

5

High-throughput

0.536

High

326434

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

0

High-throughput

0.513

High

326437

FADD
FAS-associated death domain protein

1

0

High-throughput

0.513

High

326438

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

0

High-throughput

0.513

High

326449

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

0

High-throughput

0.513

High

326430

PPAL
Lysosomal acid phosphatase

1

5

High-throughput

0.489

High

326440

MFSD8
Major facilitator superfamily domain-containing protein 8

1

6

High-throughput

0.489

High

326444

REEP6
Receptor expression-enhancing protein 6

1

5

High-throughput

0.489

High

326432

ITB4
Integrin beta-4

1

8

Small-scale

0.479

High

326447

SG196
Protein O-mannose kinase

1

2

High-throughput

0.437

High

326443

PTER
N-acetyltaurine hydrolase

2

0

High-throughput

0.328

High

326445

SHRPN
Sharpin

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025