HitPredict

Interactor 1: K2C8 (P05787)
Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8)
Gene: KRT8

Interactor 2: K1C15 (P19012)
Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)
Gene: KRT15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 25416956, 32296183, 35575683, unassigned1304
Identification Methods two hybrid, cross-linking study, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Filament~Filament
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005882 - intermediate filament
GO:0070062 - extracellular exosome
GO:0097110 - scaffold protein binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 483
Hs

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Last updated: 11Aug2025