HitPredict

Interactor 1: K2C8 (P05787)
Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8)
Gene: KRT8

Interactor 2: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.77 0.60 0.683

The method score is based on:

Property Details
Experiments 30021884, 34079125, 35575683, 39358380
Identification Methods proximity labelling technology, cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0030018 - Z disc
GO:0042383 - sarcolemma
GO:0045111 - intermediate filament cytoskeleton
GO:0070062 - extracellular exosome
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 483
Hs

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Last updated: 11Aug2025