HitPredict

Interactor 1: IFNA4 (P07351)
Interferon alpha-4 (IFN-alpha-4)
Gene: IFNA4

Interactor 2: IRF8 (P23611)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (ICSBP)
Gene: IRF8

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	17702615, 18055870
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 186 Mm			1 424
+	Mm
		456562 IFNA4_MOUSE (1-186): 4.99e-90: 263: 100.00		IRF5_MOUSE (9-422): 1.82e-165: 476: 33.04
+	Hs
		378235 IFNA1_HUMAN (1-185): 1.87e-96: 279: 58.42		IRF5_HUMAN (9-422): 1.01e-158: 458: 30.75
+	Hs
		378331 IFN14_HUMAN (1-185): 5.45e-94: 273: 54.21		IRF5_HUMAN (9-422): 1.01e-158: 458: 30.75
+	Hs
		378372 IFNB_HUMAN (1-182): 6.17e-45: 148: 28.57		IRF8_HUMAN (1-424): 0: 574: 89.67
+	Hs
		378237 IFNA1_HUMAN (1-185): 1.87e-96: 279: 58.42		IRF3_HUMAN (9-388): 6.98e-146: 423: 28.72
+	Hs
		378333 IFN14_HUMAN (1-185): 5.45e-94: 273: 54.21		IRF3_HUMAN (9-388): 6.98e-146: 423: 28.72
+	Hs
		378271 IFNA7_HUMAN (1-185): 2.37e-93: 271: 53.68		IRF3_HUMAN (9-388): 6.98e-146: 423: 28.72
+	Hs
		378252 IFNA2_HUMAN (1-185): 1.58e-90: 264: 54.74		IRF3_HUMAN (9-388): 6.98e-146: 423: 28.72
+	Mm
		456564 IFNA4_MOUSE (1-186): 4.99e-90: 263: 100.00		IRF3_MOUSE (9-396): 7.47e-136: 397: 24.69
+	Mm
		456563 IFNA4_MOUSE (1-186): 4.99e-90: 263: 100.00		IRF7_MOUSE (1-383): 5.56e-120: 358: 25.11
+	Hs
		378240 IFNA1_HUMAN (1-185): 1.87e-96: 279: 58.42		IRF7_HUMAN (12-383): 4.87e-111: 337: 21.46
+	Hs
		378340 IFN14_HUMAN (1-185): 5.45e-94: 273: 54.21		IRF7_HUMAN (12-383): 4.87e-111: 337: 21.46
+	Hs
		378274 IFNA7_HUMAN (1-185): 2.37e-93: 271: 53.68		IRF7_HUMAN (12-383): 4.87e-111: 337: 21.46
+	Hs
		378376 IFNB_HUMAN (1-182): 6.17e-45: 148: 28.57		IRF5_HUMAN (9-422): 1.01e-158: 458: 30.75
+	Hs
		378257 IFNA2_HUMAN (1-185): 1.58e-90: 264: 54.74		IRF7_HUMAN (12-383): 4.87e-111: 337: 21.46
+	Hs
		378227 IFNA1_HUMAN (1-185): 1.87e-96: 279: 58.42		IRF1_HUMAN (9-266): 9.36e-86: 266: 27.27
+	Hs
		378326 IFN14_HUMAN (1-185): 5.45e-94: 273: 54.21		IRF1_HUMAN (9-266): 9.36e-86: 266: 27.27
+	Hs
		378248 IFNA2_HUMAN (1-185): 1.58e-90: 264: 54.74		IRF1_HUMAN (9-266): 9.36e-86: 266: 27.27
+	Hs
		378355 IFNB_HUMAN (1-182): 6.17e-45: 148: 28.57		IRF1_HUMAN (9-266): 9.36e-86: 266: 27.27
+	Hs
		378356 IFNB_HUMAN (1-182): 6.17e-45: 148: 28.57		IRF2_HUMAN (9-167): 5.96e-59: 197: 37.50