HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: FCG2A (P12318)
Low affinity immunoglobulin gamma Fc region receptor II-a (IgG Fc receptor II-a) (CDw32) (Fc-gamma RII-a) (Fc-gamma-RIIa) (FcRII-a) (CD antigen CD32)
Gene: FCGR2A

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	9268059
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, protein kinase assay
Interaction Type	physical association, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 512 Hs			1 317
+	Hs
		557130 SRC_HUMAN (1-510): 0: 591: 51.97		FCG2C_HUMAN (1-317): 6.88e-78: 242: 85.17
+	Hs
		553417 SRC_HUMAN (1-510): 0: 591: 51.97		FCERA_HUMAN (20-247): 2.23e-60: 195: 32.02
+	Hs
		463845 LYN_HUMAN (1-512): 0: 621: 100.00		TUTLB_HUMAN (3-316): 4.24e-43: 160: 14.50
+	Hs
		463779 LYN_HUMAN (1-512): 0: 621: 100.00		ROBO2_HUMAN (1-314): 5.76e-39: 148: 14.61
+	Hs
		439913 LCK_HUMAN (1-512): 0: 585: 63.62		FCG3A_HUMAN (16-255): 7.02e-50: 168: 43.03
+	Hs
		557532 SRC_HUMAN (1-510): 0: 591: 51.97		TUTLB_HUMAN (3-316): 4.24e-43: 160: 14.50
+	Hs
		463325 LYN_HUMAN (1-512): 0: 621: 100.00		CD22_HUMAN (31-274): 3.12e-30: 122: 15.89
+	Hs
		463707 LYN_HUMAN (1-512): 0: 621: 100.00		KIRR1_HUMAN (29-220): 2.55e-29: 119: 19.90
+	Mm
		683104 LYN_MOUSE (1-512): 0: 621: 96.09		FCRL5_MOUSE (4-306): 4.4e-29: 118: 17.03
+	Hs
		463875 LYN_HUMAN (1-512): 0: 621: 100.00		ROBO1_HUMAN (120-317): 1.52e-22: 100: 11.93
+	Hs
		473360 HCK_HUMAN (1-512): 0: 601: 70.70		FCGR1_HUMAN (39-278): 1.7e-26: 109: 17.06
+	Mm
		465768 HCK_MOUSE (1-512): 0: 595: 69.92		FCGR1_MOUSE (30-311): 1.08e-27: 112: 18.27
+	Hs
		463317 LYN_HUMAN (1-512): 0: 621: 100.00		PECA1_HUMAN (86-287): 3.42e-11: 66: 16.51
+	Hs
		463367 LYN_HUMAN (1-512): 0: 621: 100.00		FCG2B_HUMAN (124-315): 1.69e-10: 62.9: 15.54
+	Hs
		473363 HCK_HUMAN (1-512): 0: 601: 70.70		PECA1_HUMAN (86-287): 3.42e-11: 66: 16.51
+	Hs
		557068 SRC_HUMAN (1-510): 0: 591: 51.97		PECA1_HUMAN (86-287): 3.42e-11: 66: 16.51
+	Hs
		557323 SRC_HUMAN (1-510): 0: 591: 51.97		MYLK_HUMAN (40-114): 5.39e-11: 65.6: 12.79
+	Hs
		557129 SRC_HUMAN (1-510): 0: 591: 51.97		FCG2B_HUMAN (124-315): 1.69e-10: 62.9: 15.54
+	Hs
		439937 LCK_HUMAN (1-512): 0: 585: 63.62		PECA1_HUMAN (86-287): 3.42e-11: 66: 16.51
+	Hs
		440339 FYN_HUMAN (1-510): 0: 583: 54.31		PECA1_HUMAN (86-287): 3.42e-11: 66: 16.51