Interactor 1: VIME (P08670)
Vimentin
Gene: VIM

Interactor 2: DESM (P17661)
Desmin
Gene: DES

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 28514442, 32296183, 33961781, 38334954, 31839598, 27107012, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, cross-linking study, anti tag coimmunoprecipitation, validated two hybrid, barcode fusion genetics two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Filament~Filament
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005829 - cytosol
GO:0005882 - intermediate filament
GO:0045109 - intermediate filament organization
GO:0045111 - intermediate filament cytoskeleton
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 466
Hs

1 470
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025