Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 0.60 0.771

The method score is based on:

Property Details
Experiments 25311206, 18083707, 16691492, 19250911, 23649778, 25723488, 26043024, 25969509, 28322253, 25494214, 29164995, 29147513, 29966650, 30659753, 32123815, 31857589, 32292717, 33665565, 34329467, 35366418 and 24 others

more...

Identification Methods affinity chromatography technology, pull down, x-ray crystallography, two hybrid, unspecified method, protein array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0031625 - ubiquitin protein ligase binding
GO:0070062 - extracellular exosome
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 685
Hs

1 440
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Last updated: 15 Jul 2024