HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: NBR1 (Q14596)
Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)
Gene: NBR1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.753

Property	Details
Experiments	28190767, 31699778, 38803224, 24879152, 23649778, 19427866, 19250911, 24692539
Identification Methods	pull down, affinity chromatography technology, x-ray crystallography
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 966
+	Mm
		476668 UBB_MOUSE (457-685): 2.3e-86: 275: 99.56		NBR1_MOUSE (1-966): 0: 1731: 82.15
+	Hs
		397965 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		NBR1_HUMAN (1-966): 0: 1811: 100.00
+	Mm
		476763 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		NBR1_MOUSE (1-966): 0: 1731: 82.15
+	Rn
		1119398 UBC_RAT (1-108): 1.27e-29: 127: 90.74		NBR1_RAT (1-966): 0: 1729: 81.79
+	Hs
		476380 UBC_HUMAN (1-685): 0: 846: 100.00		ILRUN_HUMAN (367-479): 4.73e-44: 163: 27.19
+	At
		1092292 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		NBR1_ARATH (363-479): 3.2e-43: 170: 33.88