HitPredict

Interactor 1: GNAI3 (P08754)
Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3)
Gene: GNAI3

Interactor 2: GBG8 (Q9UK08)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 (Gamma-9)
Gene: GNG8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005834 - heterotrimeric G-protein complex GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 354 Hs			1 70
+	Hs
		948054 GNAI1_HUMAN (1-354): 4.67e-179: 502: 93.79		GBG2_HUMAN (2-70): 8.65e-27: 94: 71.01
+	Hs
		989826 GNAI1_HUMAN (1-354): 4.67e-179: 502: 93.79		GBG3_HUMAN (3-70): 4.1e-26: 92.4: 57.35
+	Hs
		989890 GNAI1_HUMAN (1-354): 4.67e-179: 502: 93.79		GBG8_HUMAN (1-70): 9.21e-26: 91.3: 100.00
+	Hs
		893553 GNAI1_HUMAN (1-354): 4.67e-179: 502: 93.79		GBG4_HUMAN (2-70): 1.82e-25: 90.9: 60.87
+	Hs
		243468 GNAI1_HUMAN (1-354): 4.67e-179: 502: 93.79		GBG7_HUMAN (3-70): 1.04e-23: 86.2: 52.94
+	Hs
		475943 GNAI3_HUMAN (1-354): 1.48e-176: 495: 100.00		GBG3_HUMAN (3-70): 4.1e-26: 92.4: 57.35
+	Hs
		989887 GNAI1_HUMAN (1-354): 4.67e-179: 502: 93.79		GBG12_HUMAN (2-70): 4.1e-23: 84.7: 49.28
+	Hs
		475926 GNAI3_HUMAN (1-354): 1.48e-176: 495: 100.00		GBG4_HUMAN (2-70): 1.82e-25: 90.9: 60.87
+	Hs
		418632 GNAI2_HUMAN (1-354): 2.83e-174: 489: 85.92		GBG2_HUMAN (2-70): 8.65e-27: 94: 71.01
+	Hs
		893567 GNAI1_HUMAN (1-354): 4.67e-179: 502: 93.79		GBG10_HUMAN (3-70): 1.98e-21: 80.5: 48.53
+	Hs
		418646 GNAI2_HUMAN (1-354): 2.83e-174: 489: 85.92		GBG3_HUMAN (3-70): 4.1e-26: 92.4: 57.35
+	Hs
		243463 GNAI3_HUMAN (1-354): 1.48e-176: 495: 100.00		GBG7_HUMAN (3-70): 1.04e-23: 86.2: 52.94
+	Hs
		418625 GNAI2_HUMAN (1-354): 2.83e-174: 489: 85.92		GBG4_HUMAN (2-70): 1.82e-25: 90.9: 60.87
+	Hs
		989827 GNAI1_HUMAN (1-354): 4.67e-179: 502: 93.79		GBG5_HUMAN (3-70): 1.81e-20: 77.8: 44.12
+	Hs
		476053 GNAI3_HUMAN (1-354): 1.48e-176: 495: 100.00		GBG12_HUMAN (2-70): 4.1e-23: 84.7: 49.28
+	Hs
		475927 GNAI3_HUMAN (1-354): 1.48e-176: 495: 100.00		GBG10_HUMAN (3-70): 1.98e-21: 80.5: 48.53
+	Hs
		243462 GNAI2_HUMAN (1-354): 2.83e-174: 489: 85.92		GBG7_HUMAN (3-70): 1.04e-23: 86.2: 52.94
+	Hs
		475944 GNAI3_HUMAN (1-354): 1.48e-176: 495: 100.00		GBG5_HUMAN (3-70): 1.81e-20: 77.8: 44.12
+	Hs
		418626 GNAI2_HUMAN (1-354): 2.83e-174: 489: 85.92		GBG10_HUMAN (3-70): 1.98e-21: 80.5: 48.53
+	Hs
		475935 GNAI3_HUMAN (1-354): 1.48e-176: 495: 100.00		GBG11_HUMAN (4-69): 6.22e-17: 69.3: 33.33