Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 24751536, 25474007, 25847540, 26162776, 28438176, 27605430, 31300519, 36398858, 24784582
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~ubiquitin
Common GO terms GO:0002020 - protease binding
GO:0005634 - nucleus
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
and 1 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 685
Hs

1 581
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Last updated: 15 Jul 2024