Interactor 1: LYAG (P10253)
Lysosomal alpha-glucosidase (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Cleaved into: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase]
Gene: GAA

Interactor 2: GANAB (Q14697)
Neutral alpha-glucosidase AB (EC 3.2.1.207) (Alpha-glucosidase 2) (Glucosidase II subunit alpha)
Gene: GANAB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Gal_mutarotas_2~Gal_mutarotas_2, Gal_mutarotas_2~Glyco_hydro_31, Glyco_hydro_31~Glyco_hydro_31, Gal_mutarotas_2~Trefoil, Glyco_hydro_31~Trefoil
Common GO terms GO:0016020 - membrane
GO:0030246 - carbohydrate binding
GO:0043231 - intracellular membrane-bounded organelle
GO:0070062 - extracellular exosome
GO:0090599 - alpha-glucosidase activity
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 952
Hs

1 944
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024