HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UB2J1 (Q9Y385)
Ubiquitin-conjugating enzyme E2 J1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J1) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE-1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HsUBC6e)
Gene: UBE2J1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.834

Property	Details
Experiments	31518855, 27182664, 37478010
Identification Methods	enzymatic study, proximity labelling technology, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005789 - endoplasmic reticulum membrane GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 318
+	Hs
		507793 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D2_HUMAN (10-156): 6.77e-70: 215: 28.00
+	Hs
		508868 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D4_HUMAN (10-156): 6.34e-70: 215: 28.00
+	Hs
		507701 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D1_HUMAN (10-156): 1.34e-69: 214: 30.00
+	Hs
		507755 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D3_HUMAN (10-156): 2.03e-68: 211: 28.00
+	Hs
		507705 UBC_HUMAN (1-685): 0: 857: 100.00		UB2E1_HUMAN (1-155): 4.54e-64: 202: 28.48
+	Hs
		508269 UBC_HUMAN (1-685): 0: 857: 100.00		UB2J2_HUMAN (1-150): 3.35e-63: 202: 39.87
+	Hs
		508388 UBC_HUMAN (1-685): 0: 857: 100.00		UB2E3_HUMAN (2-155): 1.58e-62: 199: 26.75
+	Hs
		508456 UBC_HUMAN (1-685): 0: 857: 100.00		UB2E2_HUMAN (2-155): 4.94e-62: 197: 27.39
+	Hs
		507680 UBC_HUMAN (1-685): 0: 857: 100.00		UBE2A_HUMAN (7-154): 9.7e-61: 192: 21.85
+	Hs
		507805 UBC_HUMAN (1-685): 0: 857: 100.00		UBE2B_HUMAN (7-146): 1.16e-59: 189: 23.08
+	Hs
		507746 UBC_HUMAN (1-685): 0: 857: 100.00		UB2G2_HUMAN (7-142): 5.56e-58: 185: 26.00
+	Hs
		507779 UBC_HUMAN (1-685): 0: 857: 100.00		UB2G1_HUMAN (15-148): 2.06e-56: 182: 25.83
+	Rn
		92896 UBC_RAT (1-637): 0: 779: 98.90		UB2D1_RAT (10-156): 1.34e-69: 214: 30.00
+	Xl
		982387 Q7SY79_XENLA (77-685): 0: 752: 99.84		UB2D2_XENLA (10-156): 6.77e-70: 215: 28.00
+	Dm
		683066 Q9W418_DROME (229-685): 0: 567: 99.78		UBCD1_DROME (10-156): 6.09e-69: 213: 29.33
+	Sc
		509374 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		UBC4_YEAST (10-156): 1.61e-65: 204: 26.00
+	Sc
		509469 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		UBC6_YEAST (9-148): 3.16e-61: 197: 39.72
+	At
		762746 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC8_ARATH (10-156): 2.48e-67: 209: 29.33
+	At
		762762 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC9_ARATH (10-156): 8.02e-67: 208: 29.33
+	At
		683037 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC1_ARATH (7-154): 3.6e-60: 191: 21.19