HitPredict

Interactor 1: SPD2B (A1X283)
SH3 and PX domain-containing protein 2B (Adapter protein HOFI) (Factor for adipocyte differentiation 49) (Tyrosine kinase substrate with four SH3 domains)
Gene: SH3PXD2B

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 911 Hs			1 783
+	Hs
		51084 SPD2B_HUMAN (1-911): 3.95e-155: 481: 100.00		TRI36_HUMAN (115-771): 5.52e-100: 327: 20.16
+	Hs
		855804 VAV2_HUMAN (4-424): 1.6e-46: 182: 11.94		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		128875 P3C2A_HUMAN (7-144): 6.69e-40: 162: 29.29		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1078848 ITSN1_HUMAN (4-604): 1.16e-31: 136: 10.64		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		135789 P3C2B_HUMAN (7-143): 1.57e-22: 106: 26.09		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		235536 VINEX_HUMAN (282-616): 1.01e-16: 86.8: 11.31		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		924655 GRB2_HUMAN (130-212): 4.38e-14: 74.3: 10.84		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1167807 DNMBP_HUMAN (55-424): 1.57e-11: 70.8: 13.04		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1171144 SH3K1_HUMAN (208-609): 6.15e-11: 68.5: 13.09		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1172445 CD2AP_HUMAN (76-215): 1.14e-10: 67.3: 13.19		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		537669 NCF1_HUMAN (340-590): 1.53e-20: 97: 20.62		TRIM9_HUMAN (1-773): 6.08e-178: 529: 61.56
+	Hs
		557686 NCK1_HUMAN (137-292): 1.43e-46: 173: 27.78		TRI14_HUMAN (301-760): 3.67e-71: 241: 17.80
+	Hs
		1078906 ITSN1_HUMAN (4-604): 1.16e-31: 136: 10.64		TRIM5_HUMAN (195-774): 2.68e-77: 260: 13.90
+	Hs
		557799 NCK1_HUMAN (137-292): 1.43e-46: 173: 27.78		TRI39_HUMAN (107-616): 1.56e-17: 88.6: 11.48
+	Hs
		128802 P3C2A_HUMAN (7-144): 6.69e-40: 162: 29.29		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		208986 NCK2_HUMAN (123-313): 2.32e-32: 131: 24.88		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		135762 P3C2B_HUMAN (7-143): 1.57e-22: 106: 26.09		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		924879 GRB2_HUMAN (130-212): 4.38e-14: 74.3: 10.84		TRI39_HUMAN (107-616): 1.56e-17: 88.6: 11.48
+	Hs
		235469 VINEX_HUMAN (282-616): 1.01e-16: 86.8: 11.31		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		536781 GRB2_HUMAN (130-212): 4.38e-14: 74.3: 10.84		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77