HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PKN3 (Q6P5Z2)
Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN-beta) (Protein-kinase C-related kinase 3)
Gene: PKN3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26402096
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 889
+	Hs
		529876 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PKN1_HUMAN (27-883): 0: 965: 51.05
+	Hs
		551617 NFH_HUMAN (113-708): 1.12e-25: 115: 10.96		PKN1_HUMAN (27-883): 0: 965: 51.05
+	Hs
		529023 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		KPCA_HUMAN (383-889): 1.62e-168: 507: 34.56
+	Hs
		436592 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		KPCB_HUMAN (401-887): 1.45e-165: 499: 34.14
+	Hs
		424623 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		KPCG_HUMAN (401-889): 1.03e-157: 480: 33.33
+	Hs
		529186 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		AKT2_HUMAN (494-883): 2.12e-155: 466: 38.99
+	Hs
		529185 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		AKT1_HUMAN (494-883): 5.16e-154: 462: 38.73
+	Rn
		620044 TAU_RAT (1-758): 3.21e-76: 263: 72.11		KPCB_RAT (401-887): 9.02e-165: 497: 33.94
+	Hs
		529658 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		KPCE_HUMAN (476-887): 2.71e-149: 459: 37.59
+	Rn
		98735 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		KPCB_RAT (401-887): 9.02e-165: 497: 33.94
+	Hs
		529095 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		KS6B1_HUMAN (521-888): 1.34e-151: 458: 37.60
+	Mm
		530777 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		KPCG_MOUSE (401-889): 2.75e-157: 479: 33.33
+	Hs
		287650 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		KS6A5_HUMAN (429-815): 7.7e-96: 320: 21.39
+	Hs
		161418 KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76		AKT1_HUMAN (494-883): 5.16e-154: 462: 38.73
+	Hs
		590273 MUC1_HUMAN (39-730): 2.41e-41: 165: 11.50		KPCD_HUMAN (564-886): 1.3e-90: 303: 48.31