HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: GIT1 (Q9Y2X7)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1)
Gene: GIT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0030425 - dendrite GO:0030426 - growth cone GO:0043005 - neuron projection
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 761
+	Hs
		1490985 PCLO_HUMAN (21-757): 4.9e-30: 130: 10.00		GIT1_HUMAN (1-761): 7.44e-179: 532: 100.00
+	Hs
		1122467 PCLO_HUMAN (21-757): 4.9e-30: 130: 10.00		GIT2_HUMAN (1-758): 1.45e-149: 456: 64.26
+	Hs
		62893 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		POTEF_HUMAN (31-683): 2.45e-62: 228: 13.13
+	Hs
		530589 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		AGAP1_HUMAN (2-223): 4.14e-57: 211: 32.89
+	Hs
		530238 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		AGAP3_HUMAN (2-223): 8.36e-55: 204: 34.22
+	Hs
		529823 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		ACAP2_HUMAN (2-331): 1.63e-53: 200: 16.89
+	Hs
		207908 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		ASAP2_HUMAN (2-506): 1.52e-50: 193: 15.20
+	Hs
		529718 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		ANK3_HUMAN (62-685): 7.35e-47: 183: 10.92
+	Rn
		267188 TAU_RAT (1-758): 3.21e-76: 263: 72.11		ANK3_RAT (93-695): 1.05e-40: 164: 11.94
+	Rn
		98641 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		ANK3_RAT (93-695): 1.05e-40: 164: 11.94
+	Hs
		1129742 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		TNKS2_HUMAN (44-460): 6.79e-46: 179: 13.07
+	Hs
		1140288 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		ACAP2_HUMAN (2-331): 1.63e-53: 200: 16.89
+	Mm
		92767 D3Z656_MOUSE (129-637): 4.2e-11: 68.8: 11.79		AGAP2_MOUSE (2-223): 1.08e-48: 188: 30.18
+	Mm
		1190222 PCLO_MOUSE (31-654): 3.4e-09: 62.7: 10.40		AGAP2_MOUSE (2-223): 1.08e-48: 188: 30.18
+	Hs
		332404 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		TNKS1_HUMAN (240-723): 1.86e-21: 102: 8.93